Mucopolysaccharidosis type I
id:
mucopolysaccharidosis-type-i-320-15727041
title:
Mucopolysaccharidosis type I
text:
Mucopolysaccharidosis type I is a spectrum of diseases in the mucopolysaccharidosis family. It results in the buildup of glycosaminoglycans due to a deficiency of alpha-L iduronidase, an enzyme responsible for the degradation of GAGs in lysosomes. Without this enzyme, a buildup of dermatan sulfate and heparan sulfate occurs in the body. MPS I may present with a wide spectrum of symptoms, depending on how much functional enzyme is produced. In severe forms, symptoms appear during childhood, and e
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/Mucopolysaccharidosis_type_I
date created:
date modified:
2024-03-27T17:50:45Z
main entity:
{"identifier":"Q1906054","url":"https://www.wikidata.org/entity/Q1906054"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/ba/Dermatan_sulfate.PNG","width":1284,"height":667}
fields total:
13
integrity:
15