MSH3
id:
msh3-199-13679787
title:
MSH3
text:
DNA mismatch repair protein, MutS Homolog 3 (MSH3) is a human homologue of the bacterial mismatch repair protein MutS that participates in the mismatch repair (MMR) system. MSH3 typically forms the heterodimer MutSβ with MSH2 in order to correct long insertion/deletion loops and base-base mispairs in microsatellites during DNA synthesis. Deficient capacity for MMR is found in approximately 15% of colorectal cancers, and somatic mutations in the MSH3 gene can be found in nearly 50% of MMR-deficie
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/MSH3
date created:
date modified:
2024-01-09T15:35:45Z
main entity:
{"identifier":"Q18029418","url":"https://www.wikidata.org/entity/Q18029418"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/ab/3THX-MutSb-complex-of-MSH2-MSH3.png","width":1500,"height":1362}
fields total:
13
integrity:
15