Motifs targeted by APC/C
id:
motifs-targeted-by-apc-c-297-8693016
title:
Motifs targeted by APC/C
text:
The anaphase- promoting complex or cyclosome (APC/C) is a highly specific ubiquitin protein ligase responsible for triggering events of late mitosis. In early mitosis, Cdc20 levels rise and APC/C binds to form active APC/CCdc20. This then leads to the destruction of mitotic cyclins, securin, and other proteins to trigger chromosome separation in anaphase. In early anaphase, Cdk1 is inactivated, leading to the activation of Cdh1, the other activator subunit of APC/C. This then triggers the degrad
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Motifs_targeted_by_APC/C
date created:
date modified:
2023-11-07T18:09:43Z
main entity:
{"identifier":"Q60762652","url":"https://www.wikidata.org/entity/Q60762652"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/1/1e/APC-C_substrates.jpg","width":650,"height":531}
fields total:
13
integrity:
14