Mothers against decapentaplegic homolog 3

id: mothers-against-decapentaplegic-homolog-3-208-1107364
title: Mothers against decapentaplegic homolog 3
text: Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. SMAD3 is a member of the SMAD family of proteins. It acts as a mediator of the signals initiated by the transforming growth factor beta (TGF-β) superfamily of cytokines, which regulate cell proliferation, differentiation and death. Based on its essential role in TGF beta signaling pathway, SMAD3 has been related with tumor growth in cancer development.
brand slug: wiki
category slug: encyclopedia
description: Protein-coding gene in humans
original url: https://en.wikipedia.org/wiki/Mothers_against_decapentaplegic_homolog_3
date created: 2006-06-23T02:18:52Z
date modified: 2024-09-11T03:51:36Z
main entity: {"identifier":"Q14903974","url":"https://www.wikidata.org/entity/Q14903974"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/a9/Protein_SMAD3_PDB_1dev.png","width":1138,"height":686}
fields total: 13
integrity: 16

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