Monopolin
id:
monopolin-236-4779350
title:
Monopolin
text:
Monopolin is a protein complex that in budding yeast is composed of the four proteins CSM1, HRR25, LRS4, and MAM1. Monopolin is required for the segregation of homologous centromeres to opposite poles of a dividing cell during anaphase I of meiosis. This occurs by bridging DSN1 kinetochore proteins to sister kinetochores within the centromere to physically fuse them and allow for the microtubules to pull each homolog toward opposite mitotic spindles.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein complex
original url:
https://en.wikipedia.org/wiki/Monopolin
date created:
date modified:
2023-02-15T08:38:39Z
main entity:
{"identifier":"Q22328444","url":"https://www.wikidata.org/entity/Q22328444"}
image:
fields total:
13
integrity:
14