Monocrotaline
id:
monocrotaline-314-4095087
title:
Monocrotaline
text:
Monocrotaline (MCT) is a pyrrolizidine alkaloid that is present in plants of the Crotalaria genus. These species can synthesise MCT out of amino acids and can cause liver, lung and kidney damage in various organisms. Initial stress factors are released intracellular upon binding of MCT to BMPR2 receptors and elevated MAPK phosphorylation levels are induced, which can cause cancer in Homo sapiens. MCT can be detoxified in rats via oxidation, followed by glutathione-conjugation and hydrolysis.
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Monocrotaline
date created:
date modified:
2023-12-04T17:05:28Z
main entity:
{"identifier":"Q27107379","url":"https://www.wikidata.org/entity/Q27107379"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/2/29/Monocrotaline.svg","width":307,"height":346}
fields total:
13
integrity:
15