MODY 4

id: mody-4-312-12531098
title: MODY 4
text: MODY 4 or PDX1-MODY is a form of maturity onset diabetes of the young. MODY 4 arises from mutations of the PDX1 homeobox gene on chromosome 13. Pdx-1 is a transcription factor vital to the development of the embryonic pancreas. Even in adults it continues to play a role in the regulation and expression of genes for insulin, GLUT2, glucokinase, and somatostatin. MODY 4 is so rare that only a single family has been well-studied. A child born with pancreatic agenesis was found to be homozygous for
brand slug: wiki
category slug: encyclopedia
description: Medical condition
original url: https://en.wikipedia.org/wiki/MODY_4
date created:
date modified: 2023-12-01T20:16:19Z
main entity: {"identifier":"Q6717005","url":"https://www.wikidata.org/entity/Q6717005"}
image:
fields total: 13
integrity: 14

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