MK-386
id:
mk-386-195-3142618
title:
MK-386
text:
MK-386, also known as 4,7β-dimethyl-4-aza-5α-cholestan-3-one, is a synthetic, steroidal 5α-reductase inhibitor which was first reported in 1994 and was never marketed. It is a 4-azasteroid and a potent and selective inhibitor of 5α-reductase type I and shows high selectivity for inhibition of human 5α-reductase type I over 5α-reductase type II, with IC50 values of 0.9 nM and 154 nM, respectively. The drug was under investigation for potential treatment of androgen-dependent conditions such as ac
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/MK-386
date created:
date modified:
2023-12-09T20:22:29Z
main entity:
{"identifier":"Q39046681","url":"https://www.wikidata.org/entity/Q39046681"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/b4/MK-386_structure.svg","width":1540,"height":870}
fields total:
13
integrity:
15