Mitochondrial dicarboxylate carrier

id: mitochondrial-dicarboxylate-carrier-243-6565678
title: Mitochondrial dicarboxylate carrier
text: The mitochondrial dicarboxylate carrier (DIC) is an integral membrane protein encoded by the SLC25A10 gene in humans that catalyzes the transport of dicarboxylates such as malonate, malate, and succinate across the inner mitochondrial membrane in exchange for phosphate, sulfate, and thiosulfate by a simultaneous antiport mechanism, thus supplying substrates for the Krebs cycle, gluconeogenesis, urea synthesis, fatty acid synthesis, and sulfur metabolism.
brand slug: wiki
category slug: encyclopedia
description: Mammalian protein found in Homo sapiens
original url: https://en.wikipedia.org/wiki/Mitochondrial_dicarboxylate_carrier
date created:
date modified: 2023-08-18T08:02:09Z
main entity: {"identifier":"Q21115798","url":"https://www.wikidata.org/entity/Q21115798"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/00/Ideogram_human_chromosome_17.svg","width":474,"height":189}
fields total: 13
integrity: 15

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