Mitochondrial apoptosis-induced channel
id:
mitochondrial-apoptosis-induced-channel-275-8550906
title:
Mitochondrial apoptosis-induced channel
text:
The mitochondrial apoptosis-induced channel, is an early marker of the onset of apoptosis. This ion channel is formed on the outer mitochondrial membrane in response to certain apoptotic stimuli. MAC activity is detected by patch clamping mitochondria from apoptotic cells at the time of cytochrome c release. Members of the Bcl-2 protein family regulate apoptosis by controlling the formation of MAC: the pro-apoptotic members Bax and/or Bak form MAC, whereas the anti-apoptotic members like Bcl-2 o
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Mitochondrial_apoptosis-induced_channel
date created:
date modified:
2024-01-03T23:13:20Z
main entity:
{"identifier":"Q6881847","url":"https://www.wikidata.org/entity/Q6881847"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/en/8/85/MacModel.jpg","width":1585,"height":1290}
fields total:
13
integrity:
14