Mevalonate kinase deficiency
id:
mevalonate-kinase-deficiency-170-4878116
title:
Mevalonate kinase deficiency
text:
Mevalonate kinase deficiency (MKD) is an autosomal recessive metabolic disorder that disrupts the biosynthesis of cholesterol and isoprenoids. It is a rare genetic disorder, but a high frequency is observed in Northern European regions. Mevalonate kinase (MVK) is an enzyme involved in biosynthesis isoprenoids and is necessary for the conversion of mevalonate to mevalonate-5-phosphate in the presence of Mg2+. Downstream of this enzyme, mevalonate-5-phosphate is converted into non-sterol or sterol
brand slug:
wiki
category slug:
encyclopedia
description:
Rare genetic disease
original url:
https://en.wikipedia.org/wiki/Mevalonate_kinase_deficiency
date created:
2006-11-03T18:36:28Z
date modified:
2024-09-01T05:41:53Z
main entity:
{"identifier":"Q3043158","url":"https://www.wikidata.org/entity/Q3043158"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/d/d6/Mevalonic.jpg","width":577,"height":830}
fields total:
13
integrity:
16