MBD1
id:
mbd1-232-11774687
title:
MBD1
text:
Methyl-CpG-binding domain protein 1 is a protein that in humans is encoded by the MBD1 gene. The protein encoded by MBD1 binds to methylated sequences in DNA, and thereby influences transcription. It binds to a variety of methylated sequences, and appears to mediate repression of gene expression. It has been shown to play a role in chromatin modification through interaction with the histone H3K9 methyltransferase SETDB1. H3K9me3 is a repressive modification.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/MBD1
date created:
date modified:
2023-03-04T11:20:24Z
main entity:
{"identifier":"Q14905545","url":"https://www.wikidata.org/entity/Q14905545"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/b8/Protein_MBD1_PDB_1d9n.png","width":622,"height":520}
fields total:
13
integrity:
15