MAP3K7IP2

id: map3k7ip2-162-3425261
title: MAP3K7IP2
text: Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 is an enzyme that in humans is encoded by the MAP3K7IP2 gene. The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/R
brand slug: wiki
category slug: encyclopedia
description: Protein-coding gene in the species Homo sapiens
original url: https://en.wikipedia.org/wiki/MAP3K7IP2
date created: 2007-12-18T09:29:20Z
date modified: 2024-08-27T16:46:09Z
main entity: {"identifier":"Q18036737","url":"https://www.wikidata.org/entity/Q18036737"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/3/30/Protein_MAP3K7IP2_PDB_2dae.png","width":429,"height":411}
fields total: 13
integrity: 16

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