MAP2K4

id: map2k4-313-8051231
title: MAP2K4
text: Dual-specificity mitogen-activated protein kinase kinase 4 is an enzyme that in humans is encoded by the MAP2K4 gene. MAP2K4 encodes a dual-specificity kinase that belongs to the Ser/Thr protein kinase family. MAP2K4 phosphorylates MAP kinases in response to various environmental stresses or mitogenic stimuli. MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38 are substrates for MAP2K4, but MAPK1/ERK2 and MAPK3/ERK1 are not phosphorylated by MAP2K4. Structurally, MAP2K4 contains a kinase domain that is phos
brand slug: wiki
category slug: encyclopedia
description: Protein-coding gene in the species Homo sapiens
original url: https://en.wikipedia.org/wiki/MAP2K4
date created:
date modified: 2024-03-11T06:03:57Z
main entity: {"identifier":"Q18031446","url":"https://www.wikidata.org/entity/Q18031446"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/9/96/Protein_MAP2K4_PDB_3ALN.png","width":1200,"height":1000}
fields total: 13
integrity: 15

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