Mannomustine
id:
mannomustine-234-18248885
title:
Mannomustine
text:
Mannomustine (INN), also known as mannitol nitrogen mustard, tradename Degranol is an old alkylating antineoplastic agent from the group of nitrogen mustards. It was first synthesized and characterized in 1957 by Vargha et al. The mechanism of antineoplastic activity of mannomustine, like for all other alkylating agents, lies in its ability to alkylate DNA guanine nucleobases and, thus, to prevent uncoupling of DNA strands, which is a required step for any cell to divide. Mannomustine was, at th
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Mannomustine
date created:
date modified:
2023-04-05T23:25:09Z
main entity:
{"identifier":"Q27276910","url":"https://www.wikidata.org/entity/Q27276910"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/2/24/Mannomustine.svg","width":512,"height":376}
fields total:
13
integrity:
15