Mad2
id:
mad2-276-12526919
title:
Mad2
text:
Mad2 is an essential spindle checkpoint protein. The spindle checkpoint system is a regulatory system that restrains progression through the metaphase-to-anaphase transition. The Mad2 gene was first identified in the yeast S. cerevisiae in a screen for genes which when mutated would confer sensitivity to microtubule poisons. The human orthologues of Mad2 were first cloned in a search for human cDNAs that would rescue the microtubule poison-sensitivity of a yeast strain in which a kinetochore bin
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Mad2
date created:
date modified:
2024-04-12T15:42:16Z
main entity:
{"identifier":"Q24721471","url":"https://www.wikidata.org/entity/Q24721471"}
image:
fields total:
13
integrity:
13