Mad1
id:
mad1-275-4768155
title:
Mad1
text:
Mad1 is a non-essential protein which in yeast has a function in the spindle assembly checkpoint (SAC).
This checkpoint monitors chromosome attachment to spindle microtubules and prevents cells from starting anaphase until the spindle is built up. The name Mad refers to the observation that mutant cells are mitotic arrest deficient (MAD) during microtubule depolymerization. Mad1 recruits the anaphase inhibitor Mad2 to unattached kinetochores and is essential for Mad2-Cdc20 complex formation in v
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Mad1
date created:
date modified:
2024-04-12T15:41:02Z
main entity:
{"identifier":"Q14908544","url":"https://www.wikidata.org/entity/Q14908544"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/ac/Tetramer_Mad1_Mad2.png","width":1024,"height":768}
fields total:
13
integrity:
14