Macitentan
id:
macitentan-185-4252247
title:
Macitentan
text:
Macitentan, sold under the brand name Opsumit, is an endothelin receptor antagonist developed by Actelion and approved for the treatment of pulmonary arterial hypertension (PAH). Macitentan is a dual endothelin receptor antagonist, meaning that it acts as an antagonist of two endothelin (ET) receptor subtypes, ETA and ETB. However, macitentan has a 50-fold increased selectivity for the ETA subtype compared to the ETB subtype. Macitentan was approved for medical use in the United States in Octobe
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Macitentan
date created:
2012-08-22T11:04:08Z
date modified:
2024-09-07T16:29:56Z
main entity:
{"identifier":"Q6724151","url":"https://www.wikidata.org/entity/Q6724151"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/00/Macitentan_skeletal.svg","width":1025,"height":465}
fields total:
13
integrity:
16