Ly49

id: ly49-255-768584
title: Ly49
text: Ly49 is a family of membrane C-type lectin-like receptors expressed mainly on NK cells but also on other immune cells. Their primary role is to bind MHC-I molecules to distinguish between self healthy cells and infected or altered cells. Ly49 family is coded by Klra gene cluster and include genes for both inhibitory and activating paired receptors, but most of them are inhibitory. Inhibitory Ly49 receptors play a role in the recognition of self cells and thus maintain self-tolerance and prevent
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/Ly49
date created:
date modified: 2023-09-16T22:54:59Z
main entity: {"identifier":"Q64917496","url":"https://www.wikidata.org/entity/Q64917496"}
image:
fields total: 13
integrity: 13

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