LUBAC

id: lubac-324-2503115
title: LUBAC
text: Linear ubiquitin chain assembly complex (LUBAC) is a multi-protein complex and the only known E3 ubiquitin ligase able to conjugate ubiquitin in a head-to-tail manner to generate linear (M1-linked) polyubiquitin chains. The complex is currently known to be composed of three proteins: heme-oxidized IRP2 ubiquitin ligase 1 (HOIL-1), HOIL-1-interacting protein (HOIP), and Shank-associated RH domain-interacting protein (SHARPIN), ,. HOIL-1 and HOIP are both E3 ubiquitin ligases, however, the specifi
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/LUBAC
date created:
date modified: 2023-08-18T08:33:58Z
main entity: {"identifier":"Q21112125","url":"https://www.wikidata.org/entity/Q21112125"}
image:
fields total: 13
integrity: 13

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