Lorvotuzumab mertansine
id:
lorvotuzumab-mertansine-305-13281656
title:
Lorvotuzumab mertansine
text:
Lorvotuzumab mertansine (IMGN901) is an antibody-drug conjugate. It comprises the CD56-binding antibody, lorvotuzumab (huN901), with a maytansinoid cell-killing agent, DM1, attached using a disulfide linker, SPP. Lorvotuzumab mertansine is an experimental agent created for the treatment of CD56 positive cancers. It has been granted Orphan drug status for Merkel cell carcinoma. It has reported encouraging Phase II results for small-cell lung cancer.
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Lorvotuzumab_mertansine
date created:
date modified:
2023-05-30T01:31:42Z
main entity:
{"identifier":"Q527070","url":"https://www.wikidata.org/entity/Q527070"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/7/7d/Mertansine_mab_structure.svg","width":522,"height":289}
fields total:
13
integrity:
15