Local lymph node assay
id:
local-lymph-node-assay-200-1312688
title:
Local lymph node assay
text:
The murine local lymph node assay (LLNA) is an in vivo test for skin sensitisation. LLNA has largely superseded the guinea pig maximisation test and the Buehler test. It is considered more scientific and less cruel and has found broad scientific and regulatory acceptance. The principle underlying the LLNA is that skin sensitizers induce growth of lymphocytes in the lymph nodes draining the site of application. Lymphocyte proliferation can be measured by radiolabeling, bioluminescence or immunoas
brand slug:
wiki
category slug:
encyclopedia
description:
Toxicological test
original url:
https://en.wikipedia.org/wiki/Local_lymph_node_assay
date created:
date modified:
2022-05-23T16:14:43Z
main entity:
{"identifier":"Q6664446","url":"https://www.wikidata.org/entity/Q6664446"}
image:
fields total:
13
integrity:
14