LM22A-4
id:
lm22a-4-277-12051482
title:
LM22A-4
text:
LM22A-4 is a synthetic, selective small-molecule partial agonist of TrkB, the main receptor of brain-derived neurotrophic factor. It has been found to possess poor blood-brain-barrier penetration when administered systemically, so LM22A-4 has been given to animals instead via intranasal administration, with central nervous system TrkB activation observed. The compound produces neurogenic and neuroprotective effects in animals, and shows beneficial effects on respiration in animal models of Rett
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/LM22A-4
date created:
date modified:
2023-12-03T03:40:58Z
main entity:
{"identifier":"Q23808521","url":"https://www.wikidata.org/entity/Q23808521"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/68/LM22A-4_structure.svg","width":521,"height":278}
fields total:
13
integrity:
15