Lipophilic efficiency
id:
lipophilic-efficiency-272-4495466
title:
Lipophilic efficiency
text:
Lipophilic efficiency (LiPE), sometimes referred to as ligand-lipophilicity efficiency (LLE) is a parameter used in drug design and drug discovery to evaluate the quality of research compounds, linking potency and lipophilicity in an attempt to estimate druglikeness. For a given compound LiPE is defined as the pIC50 (or pEC50) of interest minus the LogP of the compound. In practice, calculated values such as cLogP or calculated LogD are often used instead of the measured LogP or LogD. LiPE is us
brand slug:
wiki
category slug:
encyclopedia
description:
Parameter used in drug design
original url:
https://en.wikipedia.org/wiki/Lipophilic_efficiency
date created:
date modified:
2023-08-13T21:53:19Z
main entity:
{"identifier":"Q17064984","url":"https://www.wikidata.org/entity/Q17064984"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/c/c8/LiPE_Plot.png","width":648,"height":700}
fields total:
13
integrity:
15