Ligation (molecular biology)
id:
ligation-molecular-biology-213-1972087
title:
Ligation (molecular biology)
text:
Ligation is the joining of two nucleotides, or two nucleic acid fragments, into a single polymeric chain through the action of an enzyme known as a ligase. The reaction involves the formation of a phosphodiester bond between the 3'-hydroxyl terminus of one nucleotide and the 5'-phosphoryl terminus of another nucleotide, which results in the two nucleotides being linked consecutively on a single strand. Ligation works in fundamentally the same way for both DNA and RNA. A cofactor is generally inv
brand slug:
wiki
category slug:
encyclopedia
description:
Technique for joining nucleic acid fragments
original url:
https://en.wikipedia.org/wiki/Ligation_(molecular_biology)
date created:
2013-07-18T13:09:27Z
date modified:
2024-09-12T15:19:07Z
main entity:
{"identifier":"Q11756706","url":"https://www.wikidata.org/entity/Q11756706"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/bf/Ligation.svg","width":1400,"height":900}
fields total:
13
integrity:
16