Lethal dwarfism in rabbits
id:
lethal-dwarfism-in-rabbits-201-3421339
title:
Lethal dwarfism in rabbits
text:
In the rabbit, lethal dwarfism occurs in individuals homozygous for the dwarf allele (dwdw). Homozygosity for the dwarf allele results in a lethal autosomal recessive mutation. This is caused by a loss of function (LOF) mutation in the High mobility AT-hook 2 (HMGA2) gene, spanning 12.1Kb from 44,709,089 bp to 44,721,236 bp that removes the gene promotor as well as multiple exons. This mutation greatly affects growth of homozygous embryos and homozygous kits once born. These individuals homozygo
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wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Lethal_dwarfism_in_rabbits
date created:
date modified:
2024-01-02T22:25:57Z
main entity:
{"identifier":"Q115821667","url":"https://www.wikidata.org/entity/Q115821667"}
image:
fields total:
13
integrity:
13