Leber's hereditary optic neuropathy
id:
leber-s-hereditary-optic-neuropathy-177-4342283
title:
Leber's hereditary optic neuropathy
text:
Leber's hereditary optic neuropathy (LHON) is a mitochondrially inherited degeneration of retinal ganglion cells (RGCs) and their axons that leads to an acute or subacute loss of central vision; it predominantly affects young adult males. LHON is transmitted only through the mother, as it is primarily due to mutations in the mitochondrial genome, and only the egg contributes mitochondria to the embryo. Men cannot pass on the disease to their offspring. LHON is usually due to one of three pathoge
brand slug:
wiki
category slug:
encyclopedia
description:
Mitochondrially inherited degeneration of retinal cells in human
original url:
https://en.wikipedia.org/wiki/Leber%27s_hereditary_optic_neuropathy
date created:
2005-05-15T23:55:37Z
date modified:
2024-09-04T04:03:15Z
main entity:
{"identifier":"Q1262161","url":"https://www.wikidata.org/entity/Q1262161"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/a1/Mitochondrial_inheritance.svg","width":1525,"height":1283}
fields total:
13
integrity:
16