Lapaquistat
id:
lapaquistat-269-2565314
title:
Lapaquistat
text:
Lapaquistat (TAK-475) is a cholesterol-lowering drug candidate that was abandoned before being marketed. Unlike statins, which inhibit HMG-CoA reductase, lapaquistat metabolites inhibit squalene synthase, which is further downstream in the synthesis of cholesterol. It is hoped that side effects can be reduced by not disturbing the mevalonate pathway, which is important for other biochemical molecules besides cholesterol.
However, there is increasing evidence that statins may be clinically useful
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Lapaquistat
date created:
date modified:
2023-12-11T01:48:33Z
main entity:
{"identifier":"Q6488102","url":"https://www.wikidata.org/entity/Q6488102"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/9/96/Lapaquistat.svg","width":512,"height":345}
fields total:
13
integrity:
15