L-655,708
id:
l-655-708-307-5850369
title:
L-655,708
text:
L-655,708 (FG-8094) is a nootropic drug invented in 1996 by a team working for Merck, Sharp and Dohme, that was the first compound developed which acts as a subtype-selective inverse agonist at the α5 subtype of the benzodiazepine binding site on the GABAA receptor. It acts as an inverse agonist at the α1, α2, α3 and α5 subtypes, but with much higher affinity for α5, and unlike newer α5 inverse agonists such as α5IA, L-655,708 exerts its subtype selectivity purely via higher binding affinity for
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/L-655,708
date created:
date modified:
2023-06-01T12:37:26Z
main entity:
{"identifier":"Q6456072","url":"https://www.wikidata.org/entity/Q6456072"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/7/7d/L-655%2C708.svg","width":512,"height":317}
fields total:
13
integrity:
15