Ketimine Mannich reaction
id:
ketimine-mannich-reaction-275-7156174
title:
Ketimine Mannich reaction
text:
The ketimine Mannich reaction is an asymmetric synthetic technique using differences in starting material to push a Mannich reaction to create an enantiomeric product with steric and electronic effects, through the creation of a ketimine group. Typically, this is done with a reaction with proline or another nitrogen-containing heterocycle, which control chirality with that of the catalyst. This has been theorized to be caused by the restriction of undesired (E)-isomer by preventing the ketone fr
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical reaction
original url:
https://en.wikipedia.org/wiki/Ketimine_Mannich_reaction
date created:
date modified:
2024-02-03T00:21:40Z
main entity:
{"identifier":"Q110864182","url":"https://www.wikidata.org/entity/Q110864182"}
image:
fields total:
13
integrity:
14