Kanamycin kinase

id: kanamycin-kinase-270-7873852
title: Kanamycin kinase
text: Aminoglycoside-3'-phosphotransferase (APH), also known as aminoglycoside kinase, is an enzyme that primarily catalyzes the addition of phosphate from ATP to the 3'-hydroxyl group of a 4,6-disubstituted aminoglycoside, such as kanamycin. However, APH(3') has also been found to phosphorylate at the 5'-hydroxyl group in 4,5-disubstituted aminoglycosides, which lack a 3'-hydroxyl group, and to diphosphorylate hydroxyl groups in aminoglycosides that have both 3'- and 5'-hydroxyl groups. Primarily pos
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/Kanamycin_kinase
date created:
date modified: 2023-12-03T14:33:17Z
main entity: {"identifier":"Q6360598","url":"https://www.wikidata.org/entity/Q6360598"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/e9/APHStructure.png","width":640,"height":464}
fields total: 13
integrity: 14

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