K252a
id:
k252a-193-4052974
title:
K252a
text:
K252a is an alkaloid isolated from Nocardiopsis bacteria. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1.8 and 1.7 nmol/L, respectively). At higher concentrations it is also an efficient inhibitor of serine/threonine protein kinases (IC50 of 10 to 30 nmol/L). K252a is reported to promote myogenic differentiation in C2 mouse myoblasts and has been shown to block the neuronal differentiation of rat pheochromocytoma PC12 cells
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/K252a
date created:
date modified:
2024-03-14T10:57:45Z
main entity:
{"identifier":"Q5931064","url":"https://www.wikidata.org/entity/Q5931064"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/07/%28%2B%29-K252a.svg","width":1274,"height":1122}
fields total:
13
integrity:
15