JWH-424
id:
jwh-424-316-14940680
title:
JWH-424
text:
JWH-424 is a drug from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors, but with moderate selectivity for CB2, having a Ki of 5.44nM at CB2 vs 20.9 nM at CB1. The heavier 8-iodo analogue is even more CB2 selective, with its 2-methyl derivative having 40 times selectivity for CB2. However the 1-propyl homologues in this series showed much lower affinity at both receptors, reflecting a generally reduced affinity for the 8-substituted naphthoylindol
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/JWH-424
date created:
date modified:
2023-01-11T03:12:37Z
main entity:
{"identifier":"Q15409414","url":"https://www.wikidata.org/entity/Q15409414"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/e7/JWH-424.svg","width":512,"height":766}
fields total:
13
integrity:
15