JHU-083

id: jhu-083-321-2251402
title: JHU-083
text: JHU-083 is an experimental drug which acts as a glutaminase inhibitor. It is a prodrug which is cleaved in vivo to the active form 6-diazo-5-oxo-L-norleucine. It has been researched for the treatment of various neurological conditions such as depression, Alzheimer's disease, and cerebral malaria, as well as multiple sclerosis, atherosclerosis, hepatitis, and some forms of cancer in which it was found to target senescent cells.
brand slug: wiki
category slug: encyclopedia
description: Experimental Drug
original url: https://en.wikipedia.org/wiki/JHU-083
date created:
date modified: 2023-12-01T20:37:17Z
main entity: {"identifier":"Q121553394","url":"https://www.wikidata.org/entity/Q121553394"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/7/7c/JHU-083_structure.png","width":1872,"height":798}
fields total: 13
integrity: 15

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