Janus kinase 1
id:
janus-kinase-1-289-4045384
title:
Janus kinase 1
text:
JAK1 is a human tyrosine kinase protein essential for signaling for certain type I and type II cytokines. It interacts with the common gamma chain (γc) of type I cytokine receptors, to elicit signals from the IL-2 receptor family, the IL-4 receptor family, the gp130 receptor family. It is also important for transducing a signal by type I (IFN-α/β) and type II (IFN-γ) interferons, and members of the IL-10 family via type II cytokine receptors. Jak1 plays a critical role in initiating responses to
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Janus_kinase_1
date created:
date modified:
2024-01-27T03:55:00Z
main entity:
{"identifier":"Q14914522","url":"https://www.wikidata.org/entity/Q14914522"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/a/aa/Protein_JAK1_PDB_3EYG.png","width":1200,"height":1000}
fields total:
13
integrity:
14