JAG1
id:
jag1-208-6296972
title:
JAG1
text:
Jagged1 (JAG1) is one of five cell surface proteins (ligands) that interact with four receptors in the mammalian Notch signaling pathway. The Notch signaling pathway is a highly conserved pathway that functions to establish and regulate cell fate decisions in many organ systems. Once the JAG1-NOTCH (receptor-ligand) interactions take place, a cascade of proteolytic cleavages is triggered resulting in activation of the transcription for downstream target genes. Located on human chromosome 20, the
brand slug:
wiki
category slug:
encyclopedia
description:
Protein found in humans
original url:
https://en.wikipedia.org/wiki/JAG1
date created:
2007-07-21T19:23:12Z
date modified:
2024-09-11T07:17:47Z
main entity:
{"identifier":"Q18251749","url":"https://www.wikidata.org/entity/Q18251749"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/8e/Protein_JAG1_PDB_2KB9.png","width":720,"height":360}
fields total:
13
integrity:
16