J-113,397
id:
j-113-397-309-2426074
title:
J-113,397
text:
J-113,397 is an opioid drug which was the first compound found to be a highly selective antagonist for the nociceptin receptor, also known as the ORL-1 receptor. It is several hundred times selective for the ORL-1 receptor over other opioid receptors, and its effects in animals include preventing the development of tolerance to morphine, the prevention of hyperalgesia induced by intracerebroventricular administration of nociceptin, as well as the stimulation of dopamine release in the striatum,
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/J-113,397
date created:
date modified:
2022-10-31T17:11:54Z
main entity:
{"identifier":"Q12745583","url":"https://www.wikidata.org/entity/Q12745583"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/4/44/J-113%2C397.svg","width":81,"height":145}
fields total:
13
integrity:
15