ITI-333
id:
iti-333-180-4990110
title:
ITI-333
text:
ITI-333 is a drug which has a mixed mechanism of action, acting as an antagonist at the 5-HT2A, D1 and α1A receptors, and also as a partial agonist at the μ-opioid receptor. In animal studies it blocked the head-twitch response produced by DOI and also reduced responses to morphine, while also reducing the symptoms produced by naloxone-precipitated withdrawal in opioid habituated mice. It has been developed for potential uses in treatment of opioid withdrawal and opioid use disorder.
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/ITI-333
date created:
2024-07-06T21:34:48Z
date modified:
2024-09-05T10:37:37Z
main entity:
{"identifier":"Q127685267","url":"https://www.wikidata.org/entity/Q127685267"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/5e/ITI-333_structure.png","width":769,"height":717}
fields total:
13
integrity:
16