Isolated congenital asplenia
id:
isolated-congenital-asplenia-302-12830991
title:
Isolated congenital asplenia
text:
Isolated congenital asplenia is a rare disease in humans that can cause life-threatening bacterial infections in children due to primary immunodeficiency. The infections can include pneumococal sepsis and meningitis. ICAS is a ribosomopathy, due to autosomal dominant mutation of the RPSA gene on chromosome 3p21. Unlike heterotaxy syndrome, the absent spleen (asplenia) is not associated with other structural developmental defects. In some cases the spleen is present, but very small and nonfunctio
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/Isolated_congenital_asplenia
date created:
date modified:
2024-01-05T20:53:50Z
main entity:
{"identifier":"Q25324166","url":"https://www.wikidata.org/entity/Q25324166"}
image:
fields total:
13
integrity:
14