Isocitrate dehydrogenase
id:
isocitrate-dehydrogenase-265-6917221
title:
Isocitrate dehydrogenase
text:
Isocitrate dehydrogenase (IDH) (EC 1.1.1.42) and (EC 1.1.1.41) is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2. This is a two-step process, which involves oxidation of isocitrate (a secondary alcohol) to oxalosuccinate (a ketone), followed by the decarboxylation of the carboxyl group beta to the ketone, forming alpha-ketoglutarate. In humans, IDH exists in three isoforms: IDH3 catalyzes the third step of the citric
brand slug:
wiki
category slug:
encyclopedia
description:
Class of enzymes
original url:
https://en.wikipedia.org/wiki/Isocitrate_dehydrogenase
date created:
date modified:
2024-04-03T07:05:41Z
main entity:
{"identifier":"Q261968","url":"https://www.wikidata.org/entity/Q261968"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/b2/Isocitrate_dehydrogenase_of_Escherichia_coli_Complex.jpg","width":1371,"height":919}
fields total:
13
integrity:
15