Irreversible antagonist
id:
irreversible-antagonist-201-18412965
title:
Irreversible antagonist
text:
An irreversible antagonist is a type of antagonist that binds permanently to a receptor, either by forming a covalent bond to the active site, or alternatively just by binding so tightly that the rate of dissociation is effectively zero at relevant time scales. This permanently deactivates the receptor and is usually followed by rapid internalisation and recycling of the non-functional receptor protein. Irreversible enzyme inhibitors that act similarly are clinically used and include drugs such
brand slug:
wiki
category slug:
encyclopedia
description:
Antagonist that binds permanently to a receptor
original url:
https://en.wikipedia.org/wiki/Irreversible_antagonist
date created:
date modified:
2021-11-30T06:49:31Z
main entity:
{"identifier":"Q6073768","url":"https://www.wikidata.org/entity/Q6073768"}
image:
fields total:
13
integrity:
14