Ion suppression in liquid chromatography–mass spectrometry
id:
ion-suppression-in-liquid-chromatography-mass-spectrometry-199-3688723
title:
Ion suppression in liquid chromatography–mass spectrometry
text:
Ion suppression in LC-MS and LC-MS/MS refers to reduced detector response, or signal:noise as a manifested effect of competition for ionisation efficiency in the ionisation source, between the analyte(s) of interest and other endogenous or exogenous species which have not been removed from the sample matrix during sample preparation. Ion suppression is not strictly a problem unless interfering compounds elute at the same time as the analyte of interest. In cases where ion suppressing species do
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Ion_suppression_in_liquid_chromatography%E2%80%93mass_spectrometry
date created:
date modified:
2023-10-29T02:40:39Z
main entity:
{"identifier":"Q17088083","url":"https://www.wikidata.org/entity/Q17088083"}
image:
fields total:
13
integrity:
13