Inward-rectifier potassium channel

id: inward-rectifier-potassium-channel-298-11849191
title: Inward-rectifier potassium channel
text: Inward-rectifier potassium channels (Kir, IRK) are a specific lipid-gated subset of potassium channels. To date, seven subfamilies have been identified in various mammalian cell types, plants, and bacteria. They are activated by phosphatidylinositol 4,5-bisphosphate (PIP2). The malfunction of the channels has been implicated in several diseases. IRK channels possess a pore domain, homologous to that of voltage-gated ion channels, and flanking transmembrane segments (TMSs). They may exist in the
brand slug: wiki
category slug: encyclopedia
description: Group of transmembrane proteins that passively transport potassium ions
original url: https://en.wikipedia.org/wiki/Inward-rectifier_potassium_channel
date created:
date modified: 2024-03-26T01:49:29Z
main entity: {"identifier":"Q841456","url":"https://www.wikidata.org/entity/Q841456"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/3/31/TREK_PIP2.png","width":1322,"height":1168}
fields total: 13
integrity: 15

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