Inter-alpha-trypsin inhibitor
id:
inter-alpha-trypsin-inhibitor-252-16522359
title:
Inter-alpha-trypsin inhibitor
text:
Inter-alpha-trypsin inhibitors (IαI) are plasma proteins consisting of three of four heavy chains selected from the group ITIH1, ITIH2, ITIH3, ITIH4 and one light chain selected from the group AMBP or SPINT2. They function as protease inhibitors. IαI form complexes with hyaluronan (HA), generating a serum-derived hyaluronan-associated protein (SHAP)-HA complex. The SHAP-HA complex is found in very high concentration in rheumatoid arthritic synovial fluid suggesting it has a role in the inflammat
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Inter-alpha-trypsin_inhibitor
date created:
date modified:
2020-12-17T00:53:58Z
main entity:
{"identifier":"Q6044746","url":"https://www.wikidata.org/entity/Q6044746"}
image:
fields total:
13
integrity:
13