Immunoreceptor tyrosine-based activation motif
id:
immunoreceptor-tyrosine-based-activation-motif-291-7442138
title:
Immunoreceptor tyrosine-based activation motif
text:
An immunoreceptor tyrosine-based activation motif (ITAM) is a conserved sequence of four amino acids that is repeated twice in the cytoplasmic tails of non-catalytic tyrosine-phosphorylated receptors, cell-surface proteins found mainly on immune cells. Its major role is being an integral component for the initiation of a variety of signaling pathway and subsequently the activation of immune cells, although different functions have been described, for example an osteoclast maturation.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Immunoreceptor_tyrosine-based_activation_motif
date created:
date modified:
2023-12-15T09:18:37Z
main entity:
{"identifier":"Q6005558","url":"https://www.wikidata.org/entity/Q6005558"}
image:
fields total:
13
integrity:
13