Igmesine
id:
igmesine-323-4401117
title:
Igmesine
text:
Igmesine (JO-1,784) is a sigma receptor agonist. It has neuroprotective and antidepressant-like effects in animal studies, as well as nootropic effects in models of age-related cognitive decline. In two phase II clinical trials, igmesine was found to be effective in the treatment of depression and was as active as the comparator fluoxetine. However, in a large phase III clinical trial, igmesine failed to show significant effectiveness for depression. The drug has not been developed further.
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Igmesine
date created:
date modified:
2023-08-25T15:37:36Z
main entity:
{"identifier":"Q5992117","url":"https://www.wikidata.org/entity/Q5992117"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/4/4e/Igmesine.svg","width":512,"height":253}
fields total:
13
integrity:
15