ICP8
id:
icp8-320-11135745
title:
ICP8
text:
ICP8, the herpes simplex virus type-1 single-strand DNA-binding protein, is one of seven proteins encoded in the viral genome of HSV-1 that is required for HSV-1 DNA replication. It is able to anneal to single-stranded DNA (ssDNA) as well as melt small fragments of double-stranded DNA (dsDNA); its role is to destabilize duplex DNA during initiation of replication. It differs from helicases because it is ATP- and Mg2+-independent. In cells infected with HSV-1, the DNA in those cells become coloca
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/ICP8
date created:
date modified:
2020-12-26T00:08:00Z
main entity:
{"identifier":"Q17093745","url":"https://www.wikidata.org/entity/Q17093745"}
image:
fields total:
13
integrity:
13