Icilin
id:
icilin-208-6400113
title:
Icilin
text:
Icilin (AG-3-5) is a synthetic super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Although structurally not related to menthol, it produces an extreme sensation of cold, both in humans and animals. It is almost 200 times more potent than menthol, and 2.5 times more efficacious. Despite their similar effects, icilin activates the TRPM8 receptor in a different way than menthol does. Icilin has been shown to be effective in the treatment of pruritus in an experimental model o
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Icilin
date created:
2008-03-14T13:46:00Z
date modified:
2024-09-11T08:45:23Z
main entity:
{"identifier":"Q5986473","url":"https://www.wikidata.org/entity/Q5986473"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/d/d2/Icilin.svg","width":3627,"height":1645}
fields total:
13
integrity:
16