Hyper IgM syndrome
id:
hyper-igm-syndrome-285-14038539
title:
Hyper IgM syndrome
text:
Hyper IgM syndrome is a rare primary immune deficiency disorders characterized by low or absent levels of serum IgG, IgA, IgE and normal or increased levels of serum IgM. They are resulting from mutations in the pathway from B-cell activation to isotype class switching. Patients with HIGM are usually diagnosed within the first two years of life and experience severe immunosuppression. This syndrome is also known as immunoglobulin class switch recombination (Ig-CSR) deficiencies. The most common
brand slug:
wiki
category slug:
encyclopedia
description:
Primary immune deficiency disorders
original url:
https://en.wikipedia.org/wiki/Hyper_IgM_syndrome
date created:
date modified:
2024-03-18T09:42:10Z
main entity:
{"identifier":"Q1617658","url":"https://www.wikidata.org/entity/Q1617658"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/7/77/IgM_scheme.svg","width":400,"height":384}
fields total:
13
integrity:
15