Hydroxynorketamine
id:
hydroxynorketamine-188-8894805
title:
Hydroxynorketamine
text:
Hydroxynorketamine (HNK), or 6-hydroxynorketamine, is a minor metabolite of the anesthetic, dissociative, and antidepressant drug ketamine. It is formed by hydroxylation of the intermediate norketamine, another metabolite of ketamine. As of late 2019, (2R,6R)-HNK is in clinical trials for the treatment of depression. The major metabolite of ketamine is norketamine (80%). Norketamine is secondarily converted into 4-, 5-, and 6-hydroxynorketamines (15%), mainly HNK (6-hydroxynorketamine). Ketamine
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Hydroxynorketamine
date created:
2015-06-09T23:29:29Z
date modified:
2024-09-08T19:38:07Z
main entity:
{"identifier":"Q20164362","url":"https://www.wikidata.org/entity/Q20164362"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/9/90/%282R%2C6R%29-Hydroxynorketamine_Formula_V1.svg","width":296,"height":193}
fields total:
13
integrity:
16